Non-Linear Modeling and Dose Response
Biotech, Pharmaceutical and Medical Device
This course is specifically designed to meet the analytical needs of those individuals working within FDA regulated industries. Areas of focus are regression and linear and nonlinear modeling. The course requires 8 hours of instruction.

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This course is required for those individuals that directly work with assay development and method validation. Further it may be helpful for those individuals that work with process characterization and generation of predictive models.
Engineering Statistics and Data Analysis is recommended.
Course Objectives
  1. Determine the best fit for linear models
  2. Identify when nonlinear models may be appropriate
  3. Select and fit nonlinear models
  4. Evaluate and predict performance from nonlinear models
  5. Evaluate the lack of fit from nonlinear models
  6. Determine EC50 and relative potency using JMP
Detailed Course Outline
Section I: Basics of Linear Modeling
Linear Regression Sniper Plots Fit Special
Section II: Nonlinear Models
Nonlinear platform Model selection Model evaluation Adding X factors
Section III: Bio Assay and Relative Potency
EC50 Potency and Relative Potency JMP Bioassay Addin
Section IV: Nonlinear DOE